OSTM1 Antibody
Product Specifications
Background
This gene encodes a protein that may be involved in the degradation of G proteins via the ubiquitin-dependent proteasome pathway. The encoded protein binds to members of subfamily A of the regulator of the G-protein signaling (RGS) family through an N-terminal leucine-rich region. This protein also has a central RING finger-like domain and E3 ubiquitin ligase activity. This protein is highly conserved from flies to humans. Defects in this gene may cause the autosomal recessive, infantile malignant form of osteopetrosis.
NCBI Gene ID
28962
Swiss Prot
Q86WC4
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 32-284 of human OSTM1 (NP_054747.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
HeLa
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 30-37kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
OSTM1
Positive Control 2
293T
Positive Control 3
A-549
Positive Control 4
Raji
Positive Control 5
B cells
Positive Control 6
Mouse brain
NCBI Official Name
Osteopetrosis-associated transmembrane protein 1
NCBI Organism
Homo sapiens
Other Product Names
Osteopetrosis-associated transmembrane protein 1, Chloride channel 7 beta subunit, OSTM1, GL
Tested Applications
WB
Physical Properties
Liquid
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