MC3R Antibody
Product Specifications
Background
This gene encodes a G-protein-coupled receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone that is expressed in tissues other than the adrenal cortex and melanocytes. This gene maps to the same region as the locus for benign neonatal epilepsy. Mice deficient for this gene have increased fat mass despite decreased food intake, suggesting a role for this gene product in the regulation of energy homeostasis. Mutations in this gene are associated with a susceptibility to obesity in humans.
NCBI Gene ID
4159
Swiss Prot
P41968
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human MC3R (NP_063941.3) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Immunology, Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
K-562
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 36kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
MC3R
NCBI Official Name
Melanocortin 3 receptor
NCBI Organism
Homo sapiens
Other Product Names
MC3R, MC3, melanocortin 3 receptor, OB20, OQTL, BMIQ9, MC3-R
Tested Applications
WB
Physical Properties
Liquid
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