PFN1 Antibody
Product Specifications
Background
This gene encodes a member of the profilin family of small actin-binding proteins. The encoded protein plays an important role in actin dynamics by regulating actin polymerization in response to extracellular signals. Deletion of this gene is associated with Miller-Dieker syndrome, and the encoded protein may also play a role in Huntington disease. Multiple pseudogenes of this gene are located on chromosome 1.
NCBI Gene ID
5216
Swiss Prot
P07737
Host
Rabbit
Reactivity
Human, Mouse, Rat, Monkey
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human PFN1 (NP_005013.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
COS-7
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 16kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
PFN1
Positive Control 2
HT-29
Positive Control 3
PC-12
Positive Control 4
Jurkat
NCBI Official Name
Profilin 1
NCBI Organism
Homo sapiens
Other Product Names
PFN1, ALS18
Tested Applications
WB
Physical Properties
Liquid
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