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EGFR Antibody

Product Specifications

Background

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.

NCBI Gene ID

1956

Swiss Prot

P00533

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 960-1060 of human EGFR (NP_005219.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Growth Factors, Immunology, Signal Transduction

Purification

Affinity purification

Positive Control

LO2

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 180kDa

Fragment

IgG

Symbol

EGFR

Positive Control 2

HeLa

Positive Control 3

HT-1080

Positive Control 4

Mouse liver

Positive Control 5

Rat liver

NCBI Official Name

Epidermal growth factor receptor

NCBI Organism

Homo sapiens

Other Product Names

Epidermal growth factor receptor, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1, EGFR, ERBB, ERBB1, HER1

Tested Applications

WB, IHC, IF

Physical Properties

Liquid

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