TRADD Antibody
Product Specifications
Background
The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway.
NCBI Gene ID
71609
Swiss Prot
Q15628
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of mouse TRADD
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cancer, Cell Cycle, Growth Factors, Immunology, Signal Transduction
Purification
Affinity purification
Positive Control
MCF7
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=14-023
Calculated Molecular Weight
Observed: 34kDa
Fragment
IgG
Symbol
TRADD
Positive Control 2
Jurkat
NCBI Official Name
Tumor necrosis factor receptor type 1-associated DEATH domain protein
NCBI Organism
Mus musculus
Other Product Names
Tumor necrosis factor receptor type 1-associated DEATH domain protein, TNFR1-associated DEATH domain protein, TNFRSF1A-associated via death domain, TRADD
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
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