ALDOA Antibody
Product Specifications
Background
The protein encoded by this gene, Aldolase A (fructose-bisphosphate aldolase), is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing and alternative promoter usage results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 3 and 10.
NCBI Gene ID
226
Swiss Prot
P04075
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-348 of human ALDOA (NP_908930.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
MCF7
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 43kDa
Fragment
IgG
Symbol
ALDOA
Positive Control 2
DU145
Positive Control 3
293T
Positive Control 4
HepG2
Positive Control 5
Jurkat
Positive Control 6
A-549
NCBI Official Name
Aldolase A, fructose-bisphosphate
NCBI Organism
Homo sapiens
Other Product Names
ALDOA, ALDA, MGC10942, MGC17716, MGC17767, GSD12, HEL-S-87p
Tested Applications
WB, IF
Physical Properties
Liquid
Curated Selection
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