DOT1L Antibody
Product Specifications
Background
The protein encoded by this gene is a histone methyltransferase that methylates lysine-79 of histone H3. It is inactive against free core histones, but shows significant histone methyltransferase activity against nucleosomes.
NCBI Gene ID
84444
Swiss Prot
Q8TEK3
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human DOT1L (NP_115871.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
Mouse liver
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 170kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
DOT1L
NCBI Official Name
DOT1 like histone lysine methyltransferase
NCBI Organism
Homo sapiens
Other Product Names
DOT1, KMT4, histone-lysine N-methyltransferase, H3 lysine-79 specific, DOT1 like histone H3K79 methyltransferase, DOT1-like histone methyltransferase, DOT1-like protein, DOT1-like, histone H3 methyltransferase, H3-K79-HMTase, histone H3-K79 methyltransferase, histone methyltransferase DOT1L, lysine N-methyltransferase 4
Tested Applications
WB
Physical Properties
Liquid
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