MSH2 Antibody
Product Specifications
Background
This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC) . When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
4436
Swiss Prot
P43246
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human MSH2 (NP_000242.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cancer, Cell Cycle
Purification
Affinity purification
Positive Control
NIH/3T3
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 105kDa
Fragment
IgG
Symbol
MSH2
Positive Control 2
A431
Positive Control 3
A549
Positive Control 4
Mouse testis
Positive Control 5
Mouse thymus
Positive Control 6
Mouse brain
NCBI Official Name
MutS homolog 2
NCBI Organism
Homo sapiens
Other Product Names
MSH2, FCC1, COCA1, HNPCC, LCFS2, HNPCC1
Tested Applications
WB, IP
Physical Properties
Liquid
Curated Selection
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