NF-kB p65 Antibody
Product Specifications
Background
NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
5970
Swiss Prot
Q04206
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 400 to the C-terminus of human NF-kB p65 (NP_068810.3) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cancer, Cell Cycle, Immunology, Neuroscience, Obesity, Signal Transduction, Transcription
Purification
Affinity purification
Positive Control
NIH/3T3
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 65kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
RELA
Positive Control 2
Jurkat
Positive Control 3
BT-474
Positive Control 4
Mouse lung
Positive Control 5
Mouse liver
Positive Control 6
Rat lung
NCBI Official Name
V-rel avian reticuloendotheliosis viral oncogene homolog A
NCBI Organism
Homo sapiens
Other Product Names
RELA, p65, NFKB3
Tested Applications
WB
Physical Properties
Liquid
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