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PPAR gamma Antibody

Product Specifications

Background

This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.

NCBI Gene ID

5468

Swiss Prot

P37231

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 70-170 of human PPAR gamma (NP_056953.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Neuroscience, Obesity, Signal Transduction, Stem Cell, Transcription

Purification

Affinity purification

Positive Control

A-549

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 50kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:1000IHC: 1:50 - 1:100

Symbol

PPARG

Positive Control 2

SKOV3

Positive Control 3

Mouse liver

Positive Control 4

Rat spleen

NCBI Official Name

Peroxisome proliferator-activated receptor gamma

NCBI Organism

Homo sapiens

Other Product Names

PPARG, GLM1, CIMT1, NR1C3, PPARG1, PPARG2, PPARgamma

Tested Applications

WB, IHC

Physical Properties

Liquid

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