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VEGF Receptor 2 Antibody

Product Specifications

Background

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.

NCBI Gene ID

3791

Swiss Prot

P35968

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 20-200 of human VEGF Receptor 2 (NP_002244.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Growth Factors, Immunology, Signal Transduction, Stem Cell

Purification

Affinity purification

Positive Control

Mouse heart

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=13-924

Calculated Molecular Weight

Observed: 240kDa

Fragment

IgG

Symbol

KDR

Positive Control 2

Mouse liver

Positive Control 3

Mouse lung

NCBI Official Name

Kinase insert domain receptor (a type III receptor tyrosine kinase)

NCBI Organism

Homo sapiens

Other Product Names

Vascular endothelial growth factor receptor 2, VEGFR-2, Fetal liver kinase 1, FLK-1, Kinase insert domain receptor, KDR, Protein-tyrosine kinase receptor flk-1, CD309, KDR, FLK1, VEGFR2

Tested Applications

WB, IHC

Physical Properties

Liquid

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