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ARHGEF7 Antibody

Product Specifications

Background

This gene encodes a protein that belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It forms a complex with the small GTP binding protein Rac1 and recruits Rac1 to membrane ruffles and to focal adhesions. Multiple alternatively spliced transcript variants encoding different isoforms have been observed for this gene.

NCBI Gene ID

8874

Swiss Prot

Q14155

Host

Rabbit

Reactivity

Human, Mouse, Monkey

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human ARHGEF7 (NP_001106984.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Signal Transduction

Purification

Affinity purification

Positive Control

SW620

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=13-905

Calculated Molecular Weight

Observed: 86kDa

Fragment

IgG

Symbol

ARHGEF7

Positive Control 2

Jurkat

Positive Control 3

COS-1

Positive Control 4

COS-7

Positive Control 5

MCF7

Positive Control 6

K-562

NCBI Official Name

Rho guanine nucleotide exchange factor 7

NCBI Organism

Homo sapiens

Other Product Names

Rho guanine nucleotide exchange factor 7, Beta-Pix, COOL-1, PAK-interacting exchange factor beta, p85, ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB

Tested Applications

WB, IF

Physical Properties

Liquid

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