ARHGEF7 Antibody
Product Specifications
Background
This gene encodes a protein that belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It forms a complex with the small GTP binding protein Rac1 and recruits Rac1 to membrane ruffles and to focal adhesions. Multiple alternatively spliced transcript variants encoding different isoforms have been observed for this gene.
NCBI Gene ID
8874
Swiss Prot
Q14155
Host
Rabbit
Reactivity
Human, Mouse, Monkey
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human ARHGEF7 (NP_001106984.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
SW620
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 86kDa
Fragment
IgG
Symbol
ARHGEF7
Positive Control 2
Jurkat
Positive Control 3
COS-1
Positive Control 4
COS-7
Positive Control 5
MCF7
Positive Control 6
K-562
NCBI Official Name
Rho guanine nucleotide exchange factor 7
NCBI Organism
Homo sapiens
Other Product Names
Rho guanine nucleotide exchange factor 7, Beta-Pix, COOL-1, PAK-interacting exchange factor beta, p85, ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Tested Applications
WB, IF
Physical Properties
Liquid
Curated Selection
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