UBE2K Antibody
Product Specifications
Background
The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene.
NCBI Gene ID
3093
Swiss Prot
P61086
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human UBE2K (NP_005330.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Neuroscience
Purification
Affinity purification
Positive Control
22Rv1
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 22kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
UBE2K
Positive Control 2
SKOV3
Positive Control 3
SW480
Positive Control 4
HL-60
Positive Control 5
Raji
Positive Control 6
U-251MG
NCBI Official Name
Ubiquitin-conjugating enzyme E2K
NCBI Organism
Homo sapiens
Other Product Names
UBE2K, DKFZp564C1216, DKFZp686J24237, E2-25K, HIP2, HYPG, LIG, UBC1
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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