PDIA3 Antibody
Product Specifications
Background
This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase; however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates. This protein also functions as a molecular chaperone that prevents the formation of protein aggregates.
NCBI Gene ID
2923
Swiss Prot
P30101
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 206-505 of human PDIA3 (NP_005304.3) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
NIH/3T3
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=13-834
Calculated Molecular Weight
Observed: 57kDa
Fragment
IgG
Symbol
PDIA3
Positive Control 2
MCF7
Positive Control 3
Jurkat
Positive Control 4
HepG2
Positive Control 5
LO2
Positive Control 6
Mouse brain
NCBI Official Name
Protein disulfide isomerase family A, member 3
NCBI Organism
Homo sapiens
Other Product Names
Protein disulfide isomerase family A, member 3, ERp57, ERp60, ERp61, GRP57, GRP58, HsT17083, P58, PI-PLC, 58 kDa microsomal protein, endoplasmic reticulum P58, glucose regulated protein, 58 kDa, phospholipase C-alpha, protein disulfide isomerase-associated, ERP57, ERP60
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
Curated Selection
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