RBM5 Antibody
Product Specifications
Background
This gene is a candidate tumor suppressor gene which encodes a nuclear RNA binding protein that is a component of the spliceosome A complex. The encoded protein plays a role in the induction of cell cycle arrest and apoptosis through pre-mRNA splicing of multiple target genes including the tumor suppressor protein p53. This gene is located within the tumor suppressor region 3p21.3, and may play a role in the inhibition of tumor transformation and progression of several malignancies including lung cancer.
NCBI Gene ID
10181
Swiss Prot
P52756
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human RBM5 (NP_005769.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
Affinity purification
Positive Control
U-87MG
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 120kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
RBM5
Positive Control 2
293T
Positive Control 3
HeLa
Positive Control 4
LO2
Positive Control 5
A-549
Positive Control 6
Mouse thymus
NCBI Official Name
RNA binding motif protein 5
NCBI Organism
Homo sapiens
Other Product Names
RBM5, FLJ39876, G15, H37, LUCA15, RMB5
Tested Applications
WB
Physical Properties
Liquid
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