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BAK1 Antibody [48A10]

Product Specifications

Background

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.

NCBI Gene ID

578

Swiss Prot

Q16611

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant protein of human BAK1

Clonality

Monoclonal

Clone

[48A10]

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Cell Cycle

Purification

Affinity purification

Positive Control

HeLa

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=13-783

Calculated Molecular Weight

Observed: 23kDa

Fragment

IgG

Symbol

BAK1

Positive Control 2

AGS

NCBI Official Name

BCL2-antagonist/killer 1

NCBI Organism

Homo sapiens

Other Product Names

Bak Antibody: BAK, CDN1, BCL2L7, BAK-LIKE, BAK, Apoptosis regulator BAK, Bcl2-L-7

Tested Applications

WB, IHC, IF, IP

Physical Properties

Liquid

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