NF-kB p65 Antibody [8F9G2]

Product Specifications

Background

NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

5970

Swiss Prot

Q04206

Host

Mouse

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human NF-kB p65

Clonality

Monoclonal

Clone

[8F9G2]

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Cancer, Cell Cycle, Immunology, Neuroscience, Obesity, Signal Transduction, Transcription

Purification

Affinity purification

Positive Control

HeLa

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 70kDa

Fragment

IgG

Symbol

RELA

Positive Control 2

Jurkat

Positive Control 3

HT-29

Positive Control 4

SGC-7901

Positive Control 5

NIH/3T3

Positive Control 6

Mouse liver

NCBI Official Name

V-rel avian reticuloendotheliosis viral oncogene homolog A

NCBI Organism

Homo sapiens

Other Product Names

RELA, p65, NFKB3

Tested Applications

WB, IHC, IF, IP

Physical Properties

Liquid

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