GPR143 Antibody
Product Specifications
Background
This gene encodes a protein that binds to heterotrimeric G proteins and is targeted to melanosomes in pigment cells. This protein is thought to be involved in intracellular signal transduction mechanisms. Mutations in this gene cause ocular albinism type 1, also referred to as Nettleship-Falls type ocular albinism, a severe visual disorder. A related pseudogene has been identified on chromosome Y.
NCBI Gene ID
4935
Swiss Prot
P51810
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 314-404 of human GPR143 (NP_000264.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
U-251MG
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 44kDa
Fragment
IgG
Applications Notes
WB: 1:1000 - 1:2000
Symbol
GPR143
Positive Control 2
BT-474
Positive Control 3
SW480
Positive Control 4
Mouse liver
Positive Control 5
Mouse kidney
Positive Control 6
Rat kidney
NCBI Official Name
G protein-coupled receptor 143
NCBI Organism
Homo sapiens
Other Product Names
NYS6, OA1, G-protein coupled receptor 143, ocular albinism 1, ocular albinism type 1 protein
Tested Applications
WB
Physical Properties
Liquid
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