MCM2 Antibody
Product Specifications
Background
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.
NCBI Gene ID
4171
Swiss Prot
P49736
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 360-700 of human MCM2 (NP_004517.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Stem Cell
Purification
Affinity purification
Positive Control
SW480
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=13-723
Calculated Molecular Weight
Observed: 130kDa
Fragment
IgG
Symbol
MCM2
Positive Control 2
SH-SY5Y
Positive Control 3
Raji
Positive Control 4
A-549
Positive Control 5
HeLa
Positive Control 6
HL-60
NCBI Official Name
Minichromosome maintenance complex component 2
NCBI Organism
Homo sapiens
Other Product Names
MCM2, BM28, CCNL1, CDCL1, cdc19, D3S3194, MITOTIN
Tested Applications
WB, IHC
Physical Properties
Liquid
Curated Selection
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