Radafaxine (hydrochloride)
Radafaxine hydrochloride (GW-353162A) is a DAT (dopamine transporter) and NET (norepinephrine transporter) transporters inhibitor, and nAChR family modulator. Radafaxine hydrochloride (GW-353162A) is a potent metabolite of bupropion and selective for inhibiting the reuptake of norepinephrine over dopamine[1][2][3].
Product Specifications
CAS Number
106083-71-0
Product Name Alternative
(S, S) -Hydroxybupropion (hydrochloride) ; GW-353162A; BW-306U
UNSPSC
12352005
Hazard Statement
H319, H402
Target
Monoamine Transporter
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Radafaxine-hydrochloride.html
Purity
99.01
Solubility
DMSO : 25 mg/mL (ultrasonic) |H2O : 25 mg/mL (ultrasonic)
Smiles
O[C@]1(C2=CC=CC(Cl)=C2)[C@H](C)NC(C)(C)CO1.[H]Cl
Molecular Formula
C13H19Cl2NO2
Molecular Weight
292.21
Precautions
H319, H402
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
Frequently Asked Questions
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