LGR5 Antibody
Product Specifications
Background
The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
8549
Swiss Prot
O75473
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 824-907 of human LGR5 (NP_003658.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction, Stem Cell
Purification
Affinity purification
Positive Control
HT-29
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=13-711
Calculated Molecular Weight
Observed: 105kDa
Fragment
IgG
Symbol
LGR5
Positive Control 2
HepG2
Positive Control 3
SKOV3
Positive Control 4
A-431
Positive Control 5
Mouse brain
Positive Control 6
Rat brain
NCBI Official Name
Leucine-rich repeat-containing G-protein coupled receptor 5
NCBI Organism
Homo sapiens
Other Product Names
Leucine-rich repeat-containing G-protein coupled receptor 5, G-protein coupled receptor 49, G-protein coupled receptor 67, G-protein coupled receptor HG38, LGR5, GPR49, GPR67
Tested Applications
WB, IF
Physical Properties
Liquid
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