MEGF10 Antibody
Product Specifications
Background
This gene encodes a member of the multiple epidermal growth factor-like domains protein family. The encoded protein plays a role in cell adhesion, motility and proliferation, and is a critical mediator of apoptotic cell phagocytosis as well as amyloid-beta peptide uptake in the brain. Expression of this gene may be associated with schizophrenia, and mutations in this gene are a cause of early-onset myopathy, areflexia, respiratory distress, and dysphagia (EMARDD) as well as congenital myopathy with minicores. Alternatively spliced transcript variants have been observed for this gene.
NCBI Gene ID
84466
Swiss Prot
Q96KG7
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 26-160 of human MEGF10 (NP_001295048.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cell Cycle, Stem Cell
Purification
Affinity purification
Positive Control
U-251MG
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 122kDa
Fragment
IgG
Symbol
MEGF10
Positive Control 2
HT-29
Positive Control 3
MCF7
Positive Control 4
Mouse brain
Positive Control 5
Mouse liver
Positive Control 6
Rat brain
NCBI Official Name
Multiple EGF like domains 10
NCBI Organism
Homo sapiens
Other Product Names
EMARDD, multiple epidermal growth factor-like domains protein 10
Tested Applications
WB, IF
Physical Properties
Liquid
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