GLRB Antibody
Product Specifications
Background
This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants.
NCBI Gene ID
2743
Swiss Prot
P48167
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 23-265 of human GLRB (NP_000815.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
U-251MG
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 58kDa
Fragment
IgG
Applications Notes
WB: 1:1000 - 1:2000
Symbol
GLRB
Positive Control 2
NCI-H460
Positive Control 3
HT-1080
Positive Control 4
THP-1
Positive Control 5
Mouse brain
Positive Control 6
Mouse liver
NCBI Official Name
Glycine receptor subunit beta
NCBI Organism
Homo sapiens
Other Product Names
Glycine receptor subunit beta, Glycine receptor 58 kDa subunit, GLRB
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
127267-ML650 100 µL
GEMIN6 (Gem-associated Protein 6, Gemin-6, SIP2, FLJ23459) (MaxLight 650)
Ask
View Details 
