GABBR1 Antibody

Product Specifications

Background

This gene encodes a receptor for gamma-aminobutyric acid (GABA), which is the main inhibitory neurotransmitter in the mammalian central nervous system. This receptor functions as a heterodimer with GABA (B) receptor 2. Defects in this gene may underlie brain disorders such as schizophrenia and epilepsy. Alternative splicing generates multiple transcript variants, but the full-length nature of some of these variants has not been determined.

NCBI Gene ID

2550

Swiss Prot

Q9UBS5

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 200-460 of human GABBR1 (NP_068703.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction

Purification

Affinity purification

Positive Control

DU145

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 95kDa

Fragment

IgG

Applications Notes

WB: 1:1000 - 1:2000

Symbol

GABBR1

Positive Control 2

HT-1080

Positive Control 3

HT-29

Positive Control 4

HeLa

Positive Control 5

Mouse brain

Positive Control 6

Mouse spinal cord

NCBI Official Name

Gamma-aminobutyric acid type B receptor subunit 1

NCBI Organism

Homo sapiens

Other Product Names

GABABR1-3, GB1, GPRC3A, GABBR1, gamma-aminobutyric acid type B receptor subunit 1, GABA-B receptor, R1 subunit, gamma-aminobutyric acid (GABA) B receptor, 1, seven transmembrane helix receptor