ASIC2 Antibody
Product Specifications
Background
This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene may play a role in neurotransmission. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 3 has been observed to co-assemble into proton-gated channels sensitive to gadolinium. Alternative splicing has been observed at this locus and two variants, encoding distinct isoforms, have been identified.
NCBI Gene ID
40
Swiss Prot
Q16515
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 120-400 of human ASIC2 (NP_001085.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cell Cycle, Neuroscience
Purification
Affinity purification
Positive Control
U-251MG
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 58kDa
Fragment
IgG
Applications Notes
WB: 1:1000 - 1:2000
Symbol
ASIC2
Positive Control 2
293T
Positive Control 3
Mouse brain
Positive Control 4
Rat brain
Positive Control 5
Rat lung
NCBI Official Name
Acid-sensing (proton-gated) ion channel 2
NCBI Organism
Homo sapiens
Other Product Names
ACCN1, ACCN, BNC1, MDEG, ACCN1, BNaC1, ASIC2a, hBNaC1
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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