PHGDH Antibody
Product Specifications
Background
This gene encodes the enzyme which is involved in the early steps of L-serine synthesis in animal cells. L-serine is required for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been found in a family with congenital microcephaly, psychomotor retardation and other symptoms. Multiple alternatively spliced transcript variants have been found, however the full-length nature of most are not known.
NCBI Gene ID
26227
Swiss Prot
O43175
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 264-533 of human PHGDH (NP_006614.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
U-87MG
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 57kDa
Fragment
IgG
Symbol
PHGDH
Positive Control 2
B cells
Positive Control 3
HeLa
Positive Control 4
SKOV3
Positive Control 5
Mouse brain
Positive Control 6
Rat spinal cord
NCBI Official Name
Phosphoglycerate dehydrogenase
NCBI Organism
Homo sapiens
Other Product Names
PHGDH, 3-PGDH, 3PGDH, PGDH, Phosphoglycerate dehydrogenase, PDG, PGAD, PGDH3
Tested Applications
WB, IHC
Physical Properties
Liquid
Curated Selection
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