PEX6 Antibody
Product Specifications
Background
This gene encodes a member of the AAA (ATPases associated with diverse cellular activities) family of ATPases. This member is a predominantly cytoplasmic protein, which plays a direct role in peroxisomal protein import and is required for PTS1 (peroxisomal targeting signal 1, a C-terminal tripeptide of the sequence ser-lys-leu) receptor activity. Mutations in this gene cause peroxisome biogenesis disorders of complementation group 4 and complementation group 6. Several transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
5190
Swiss Prot
Q13608
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 741-980 of human PEX6 (NP_000278.3) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
Affinity purification
Positive Control
BT-474
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 104kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
PEX6
Positive Control 2
K-562
Positive Control 3
Mouse liver
Positive Control 4
Mouse brain
NCBI Official Name
Peroxisomal biogenesis factor 6
NCBI Organism
Homo sapiens
Other Product Names
PEX6, peroxisomal biogenesis factor 6, PAF-2, PAF2, PXAAA1, peroxisomal AAA-type ATPase 1, peroxisome biogenesis factor 6
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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