PLB1 Antibody
Product Specifications
Background
This gene encodes a membrane-associated phospholipase that displays lysophospholipase and phospholipase A2 activities through removal of sn-1 and sn-2 fatty acids of glycerophospholipids. In addition, it displays lipase and retinyl ester hydrolase activities. The encoded protein is highly conserved and is composed of a large, glycosylated extracellular domain composed of four tandem homologous domains, followed by a hydrophobic segment that anchors the enzyme to the membrane and a short C-terminal cytoplasmic tail. This gene has been identified as a candidate rheumatoid arthritis risk gene.
NCBI Gene ID
151056
Swiss Prot
Q6P1J6
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1110-1415 of human PLB1 (NP_694566.4) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
Affinity purification
Positive Control
A-431
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 170kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
PLB1
Positive Control 2
U-87MG
Positive Control 3
HL-60
Positive Control 4
HT-29
Positive Control 5
Mouse testis
Positive Control 6
Mouse lung
NCBI Official Name
Phospholipase B1
NCBI Organism
Homo sapiens
Other Product Names
PLB, PLB/LIP, phospholipase B1, membrane-associated, lysophospholipase, phospholipase A2, phospholipase B/lipase
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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