MMP16 Antibody
Product Specifications
Background
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The encoded protein activates MMP2 by cleavage. This gene was once referred to as MT-MMP2, but was renamed as MT-MMP3 or MMP16.
NCBI Gene ID
4325
Swiss Prot
P51512
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 290-565 of human MMP16 (NP_005932.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle
Purification
Affinity purification
Positive Control
U-87MG
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 60kDa
Fragment
IgG
Symbol
MMP16
Positive Control 2
HT-29
Positive Control 3
MCF7
Positive Control 4
HT-1080
Positive Control 5
Mouse brain
Positive Control 6
Rat brain
NCBI Official Name
Matrix metallopeptidase 16 (membrane-inserted)
NCBI Organism
Homo sapiens
Other Product Names
MMP16, C8orf57, MMP-X2, MT-MMP3, MT3MMP, MT-MMP 3, MT-MMP2, MT2-MMP, Matrix metalloproteinase-16, Membrane type 3-MMP, MMP-16, MMPX2, MT3-MMP, MTMMP3
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
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