ERAL1 Antibody
Product Specifications
Background
The protein encoded by this gene is a GTPase that localizes to the mitochondrion. The encoded protein binds to the 3' terminal stem loop of 12S mitochondrial rRNA and is required for proper assembly of the 28S small mitochondrial ribosomal subunit. Deletion of this gene has been shown to cause mitochondrial dysfunction, growth retardation, and apoptosis. Several transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
26284
Swiss Prot
O75616
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 198-437 of human ERAL1 (NP_005693.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
Affinity purification
Positive Control
SKOV3
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=13-618
Calculated Molecular Weight
Observed: 48kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
ERAL1
Positive Control 2
HeLa
Positive Control 3
U-87MG
Positive Control 4
NCI-H460
Positive Control 5
Mouse kidney
Positive Control 6
Mouse heart
NCBI Official Name
Era-like 12S mitochondrial rRNA chaperone 1
NCBI Organism
Homo sapiens
Other Product Names
ERAL1, ERA, H-ERA, ERAL1A, HERA-A, HERA-B
Tested Applications
WB
Physical Properties
Liquid
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