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GRK4 Antibody

Product Specifications

Background

This gene encodes a member of the guanine nucleotide-binding protein (G protein) -coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating its deactivation. This gene has been linked to both genetic and acquired hypertension. Several transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

2868

Swiss Prot

P32298

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 359-578 of human GRK4 (NP_892027.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

Affinity purification

Positive Control

U-87MG

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 72kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

GRK4

Positive Control 2

BT-474

Positive Control 3

HeLa

Positive Control 4

Mouse brain

Positive Control 5

Mouse lung

Positive Control 6

Rat brain

NCBI Official Name

G protein-coupled receptor kinase 4

NCBI Organism

Homo sapiens

Other Product Names

GRK4, GPRK2L, GPRK4, GRK4a, IT11

Tested Applications

WB

Physical Properties

Liquid

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