MMACHC Antibody
Product Specifications
Background
The exact function of the protein encoded by this gene is not known, however, its C-terminal region shows similarity to TonB, a bacterial protein involved in energy transduction for cobalamin (vitamin B12) uptake. Hence, it is postulated that this protein may have a role in the binding and intracellular trafficking of cobalamin. Mutations in this gene are associated with methylmalonic aciduria and homocystinuria type cblC.
NCBI Gene ID
25974
Swiss Prot
Q9Y4U1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 63-282 of human MMACHC (NP_056321.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
Affinity purification
Positive Control
Raji
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 32kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
MMACHC
Positive Control 2
Jurkat
Positive Control 3
Mouse kidney
Positive Control 4
Rat brain
NCBI Official Name
Methylmalonic aciduria and homocystinuria type C protein
NCBI Organism
Homo sapiens
Other Product Names
Methylmalonic aciduria and homocystinuria type C protein, MMACHC
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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