SLAMF6 Antibody
Product Specifications
Background
The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs) . It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
NCBI Gene ID
114836
Swiss Prot
Q96DU3
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human SLAMF6
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
Affinity purification
Positive Control
Jurkat
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 70kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
SLAMF6
Positive Control 2
Mouse lung
Positive Control 3
Mouse spleen
Positive Control 4
Rat liver
NCBI Official Name
SLAM family member 6
NCBI Organism
Homo sapiens
Other Product Names
SLAMF6, KALI, KALIb, Ly108, MGC104953, NTB-A, NTBA, SF2000, CD352
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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