CABLES1 Antibody
Product Specifications
Background
This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127) .Multiple transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
91768
Swiss Prot
Q8TDN4
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-368 of human CABLES1 (NP_612384.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
Affinity purification
Positive Control
MCF7
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 67kDa
Fragment
IgG
Symbol
CABLES1
Positive Control 2
HT-29
Positive Control 3
A-549
Positive Control 4
HL-60
Positive Control 5
HeLa
Positive Control 6
Mouse brain
NCBI Official Name
Cdk5 and Abl enzyme substrate 1
NCBI Organism
Homo sapiens
Other Product Names
CABL1, CABLES, HsT2563, IK3-1, CDK5 and ABL1 enzyme substrate 1, interactor with CDK3 1
Tested Applications
WB, IHC
Physical Properties
Liquid
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