ENO1 Antibody, KO Validated
Product Specifications
Background
This gene encodes alpha-enolase, one of three enolase isoenzymes found in mammals. Each isoenzyme is a homodimer composed of 2 alpha, 2 gamma, or 2 beta subunits, and functions as a glycolytic enzyme. Alpha-enolase in addition, functions as a structural lens protein (tau-crystallin) in the monomeric form. Alternative splicing of this gene results in a shorter isoform that has been shown to bind to the c-myc promoter and function as a tumor suppressor. Several pseudogenes have been identified, including one on the long arm of chromosome 1. Alpha-enolase has also been identified as an autoantigen in Hashimoto encephalopathy.
NCBI Gene ID
2023
Swiss Prot
P06733
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-434 of human ENO1 (NP_001419.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Validation
Antibody is Knockout validated.
Field of Research
Cancer, Signal Transduction, Transcription
Purification
Affinity purification
Positive Control
PC-3
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=13-583
Calculated Molecular Weight
Observed: 47kDa
Fragment
IgG
Symbol
ENO1
Positive Control 2
Ramos
Positive Control 3
NCI-H460
Positive Control 4
HeLa
Positive Control 5
THP-1
Positive Control 6
Mouse kidney
NCBI Official Name
Enolase 1, (alpha)
NCBI Organism
Homo sapiens
Other Product Names
ENO1, NNE, PPH, MPB1, ENO1L1
Tested Applications
WB, IF, IP
Physical Properties
Liquid
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