LEPRE1 Antibody
Product Specifications
Background
This gene encodes an enzyme that is a member of the collagen prolyl hydroxylase family. These enzymes are localized to the endoplasmic reticulum and their activity is required for proper collagen synthesis and assembly. Mutations in this gene are associated with osteogenesis imperfecta type VIII. Three alternatively spliced transcript variants encoding different isoforms have been described. Other variants may exist, but their biological validity has not been determined.
NCBI Gene ID
64175
Swiss Prot
Q32P28
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 497-736 of human LEPRE1 (NP_071751.3) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
A375
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=13-580
Calculated Molecular Weight
Observed: 100kDa
Fragment
IgG
Applications Notes
WB: 1:1000 - 1:2000
Symbol
LEPRE1
Positive Control 2
NCI-H460
Positive Control 3
HT-29
Positive Control 4
HeLa
Positive Control 5
SKOV3
NCBI Official Name
Prolyl 3-hydroxylase 1
NCBI Organism
Homo sapiens
Other Product Names
GROS1, LEPRE1, OI8, prolyl 3-hydroxylase 1, growth suppressor 1, leprecan, leucine proline-enriched proteoglycan (leprecan) 1, leucine- and proline-enriched proteoglycan 1, procollagen-proline 3-dioxygenase
Tested Applications
WB
Physical Properties
Liquid
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