LEPRE1 Antibody

Product Specifications

Background

This gene encodes an enzyme that is a member of the collagen prolyl hydroxylase family. These enzymes are localized to the endoplasmic reticulum and their activity is required for proper collagen synthesis and assembly. Mutations in this gene are associated with osteogenesis imperfecta type VIII. Three alternatively spliced transcript variants encoding different isoforms have been described. Other variants may exist, but their biological validity has not been determined.

NCBI Gene ID

64175

Swiss Prot

Q32P28

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 497-736 of human LEPRE1 (NP_071751.3) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction

Purification

Affinity purification

Positive Control

A375

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 100kDa

Fragment

IgG

Applications Notes

WB: 1:1000 - 1:2000

Symbol

LEPRE1

Positive Control 2

NCI-H460

Positive Control 3

HT-29

Positive Control 4

HeLa

Positive Control 5

SKOV3

NCBI Official Name

Prolyl 3-hydroxylase 1

NCBI Organism

Homo sapiens

Other Product Names

GROS1, LEPRE1, OI8, prolyl 3-hydroxylase 1, growth suppressor 1, leprecan, leucine proline-enriched proteoglycan (leprecan) 1, leucine- and proline-enriched proteoglycan 1, procollagen-proline 3-dioxygenase