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ASPN Antibody

Product Specifications

Background

This gene encodes a cartilage extracellular protein that is member of the small leucine-rich proteoglycan family. The encoded protein may regulate chondrogenesis by inhibiting transforming growth factor-beta 1-induced gene expression in cartilage. This protein also binds collagen and calcium and may induce collagen mineralization. Polymorphisms in the aspartic acid repeat region of this gene are associated with a susceptibility to osteoarthritis, and also with intervertebral disc disease. Alternative splicing of this gene results in multiple transcript variants.

NCBI Gene ID

54829

Swiss Prot

Q9BXN1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 100-379 of human ASPN (NP_060150.4) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction

Purification

Affinity purification

Positive Control

HeLa

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 43kDa

Fragment

IgG

Symbol

ASPN

Positive Control 2

SKOV3

Positive Control 3

SGC-7901

Positive Control 4

Mouse heart

Positive Control 5

Mouse stomach

Positive Control 6

Rat heart

NCBI Official Name

Asporin

NCBI Organism

Homo sapiens

Other Product Names

ASPN, FLJ20129, PLAP1, SLRR1C, OS3, PLAP-1

Tested Applications

WB, IF

Physical Properties

Liquid

Frequently Asked Questions

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