ASPN Antibody
Product Specifications
Background
This gene encodes a cartilage extracellular protein that is member of the small leucine-rich proteoglycan family. The encoded protein may regulate chondrogenesis by inhibiting transforming growth factor-beta 1-induced gene expression in cartilage. This protein also binds collagen and calcium and may induce collagen mineralization. Polymorphisms in the aspartic acid repeat region of this gene are associated with a susceptibility to osteoarthritis, and also with intervertebral disc disease. Alternative splicing of this gene results in multiple transcript variants.
NCBI Gene ID
54829
Swiss Prot
Q9BXN1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 100-379 of human ASPN (NP_060150.4) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
HeLa
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 43kDa
Fragment
IgG
Symbol
ASPN
Positive Control 2
SKOV3
Positive Control 3
SGC-7901
Positive Control 4
Mouse heart
Positive Control 5
Mouse stomach
Positive Control 6
Rat heart
NCBI Official Name
Asporin
NCBI Organism
Homo sapiens
Other Product Names
ASPN, FLJ20129, PLAP1, SLRR1C, OS3, PLAP-1
Tested Applications
WB, IF
Physical Properties
Liquid
Curated Selection
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