INVS Antibody
Product Specifications
Background
This gene encodes a protein containing multiple ankyrin domains and two IQ calmodulin-binding domains. The encoded protein may function in renal tubular development and function, and in left-right axis determination. This protein interacts with nephrocystin and infers a connection between primary cilia function and left-right axis determination. A similar protein in mice interacts with calmodulin. Mutations in this gene have been associated with nephronophthisis type 2. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
NCBI Gene ID
27130
Swiss Prot
Q9Y283
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human INVS (NP_055240.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Neuroscience, Signal Transduction, Stem Cell
Purification
Affinity purification
Positive Control
293T
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 120kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
INVS
Positive Control 2
K-562
Positive Control 3
Mouse liver
Positive Control 4
Mouse kidney
NCBI Official Name
Inversin
NCBI Organism
Homo sapiens
Other Product Names
INV, NPH2, NPHP2, inversin, inversion of embryo turning homolog, inversion of embryonic turning, nephrocystin-2
Tested Applications
WB
Physical Properties
Liquid
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