HTR3B Antibody
Product Specifications
Background
The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit B of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It is not functional as a homomeric complex, but a pentaheteromeric complex with subunit A (HTR3A) displays the full functional features of this receptor.
NCBI Gene ID
9177
Swiss Prot
O95264
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 22-238 of human HTR3B (NP_006019.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Obesity, Signal Transduction
Purification
Affinity purification
Positive Control
U-87MG
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 50kDa
Fragment
IgG
Applications Notes
WB: 1:1000 - 1:2000
Symbol
HTR3B
Positive Control 2
A-549
Positive Control 3
HepG2
Positive Control 4
293T
NCBI Official Name
5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
NCBI Organism
Homo sapiens
Other Product Names
HTR3B, 5-HT3B
Tested Applications
WB
Physical Properties
Liquid
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