ADAM19 Antibody

Product Specifications

Background

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a type I transmembrane protein and serves as a marker for dendritic cell differentiation. It has been demonstrated to be an active metalloproteinase, which may be involved in normal physiological processes such as cell migration, cell adhesion, cell-cell and cell-matrix interactions, and signal transduction. It is proposed to play a role in pathological processes, such as cancer, inflammatory diseases, renal diseases, and Alzheimer's disease.

NCBI Gene ID

8728

Swiss Prot

Q9H013

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 203-460 of human ADAM19 (NP_150377.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Signal Transduction

Purification

Affinity purification

Positive Control

HT-1080

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 72kDa

Fragment

IgG

Symbol

ADAM19

Positive Control 2

SW480

Positive Control 3

NIH/3T3

Positive Control 4

Mouse heart

Positive Control 5

Mouse lung

Positive Control 6

Mouse liver

NCBI Official Name

ADAM metallopeptidase domain 19

NCBI Organism

Homo sapiens

Other Product Names

ADAM19, ADAM metallopeptidase domain 19, MADDAM, MLTNB, ADAM 19, a disintegrin and metalloproteinase domain 19 (meltrin beta), disintegrin and metalloproteinase domain-containing protein 19, meltrin beta, meltrin-beta, metalloprotease and disintegrin dend