SPG7 Antibody
Product Specifications
Background
This gene encodes a mitochondrial metalloprotease protein that is a member of the AAA family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. Mutations in this gene cause autosomal recessive spastic paraplegia 7. Two transcript variants encoding distinct isoforms have been identified.
NCBI Gene ID
6687
Swiss Prot
Q9UQ90
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human SPG7 (NP_003110.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Neuroscience
Purification
Affinity purification
Positive Control
U-87MG
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 88kDa
Fragment
IgG
Symbol
SPG7
Positive Control 2
MCF7
Positive Control 3
HT-29
Positive Control 4
K-562
Positive Control 5
Mouse brain
Positive Control 6
Mouse kidney
NCBI Official Name
Paraplegin
NCBI Organism
Homo sapiens
Other Product Names
Paraplegin, 3424-, Spastic paraplegia 7 protein, SPG7, CAR, CMAR, PGN
Tested Applications
WB, IHC
Physical Properties
Liquid
Curated Selection
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