SH3BP2 Antibody
Product Specifications
Background
The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases , and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
6452
Swiss Prot
P78314
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 392-561 of human SH3BP2 (NP_001116153.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
Affinity purification
Positive Control
A-549
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 75kDa/80kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
SH3BP2
Positive Control 2
Mouse spleen
Positive Control 3
Mouse lung
NCBI Official Name
SH3-domain binding protein 2
NCBI Organism
Homo sapiens
Other Product Names
SH3BP2, 3BP2, CRBM, CRPM, FLJ42079, RES4-23, 3BP-2
Tested Applications
WB
Physical Properties
Liquid
Frequently Asked Questions
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