MAN2A1 Antibody

Product Specifications

Background

This gene encodes a glycosyl hydrolase that localizes to the Golgi and catalyzes the final hydrolytic step in the asparagine-linked oligosaccharide (N-glycan) maturation pathway. Mutations in the mouse homolog of this gene have been shown to cause a systemic autoimmune disease similar to human systemic lupus erythematosus.

NCBI Gene ID

4124

Swiss Prot

Q16706

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 865-1144 of human MAN2A1 (NP_002363.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

Affinity purification

Positive Control

LO2

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 131-170kDa

Fragment

IgG

Applications Notes

WB: 1:1000 - 1:2000

Symbol

MAN2A1

Positive Control 2

MCF7

Positive Control 3

NCI-H460

Positive Control 4

HT-29

Positive Control 5

HT-1080

Positive Control 6

Mouse liver

NCBI Official Name

Mannosidase, alpha, class 2A, member 1

NCBI Organism

Homo sapiens

Other Product Names

MAN2A1, mannosidase, alpha, class 2A, member 1, GOLIM7, MANA2, MANII, Golgi alpha-mannosidase II, golgi integral membrane protein 7, alpha type II, mannosyl-oligosaccharide 1, 3-1, 6-alpha-mannosidase