IGFALS Antibody

Product Specifications

Background

The protein encoded by this gene is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty. Three transcript variants encoding two different isoforms have been found for this gene.

NCBI Gene ID

3483

Swiss Prot

P35858

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 396-605 of human IGFALS (NP_004961.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Growth Factors, Signal Transduction

Purification

Affinity purification

Positive Control

Mouse lung

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 66kDa/72kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

IGFALS

Positive Control 2

Rat liver

NCBI Official Name

Insulin-like growth factor binding protein, acid labile subunit

NCBI Organism

Homo sapiens

Other Product Names

ALS, INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN COMPLEX ACID LABILE CHAIN, ALS, insulin-like growth factor binding protein, acid labile subunit, IGFALS Official Symbol: IGFALS