EPHA8 Antibody

Product Specifications

Background

This gene encodes a member of the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. The protein encoded by this gene functions as a receptor for ephrin A2, A3 and A5 and plays a role in short-range contact-mediated axonal guidance during development of the mammalian nervous system.

NCBI Gene ID

2046

Swiss Prot

P29322

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 28-300 of human EPHA8 (NP_001006944.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction

Purification

Affinity purification

Positive Control

U-87MG

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 111kDa

Fragment

IgG

Applications Notes

WB: 1:1000 - 1:2000

Symbol

EPHA8

Positive Control 2

B cells

Positive Control 3

Mouse liver

Positive Control 4

Mouse heart

Positive Control 5

Mouse pancreas

Positive Control 6

Mouse brain

NCBI Official Name

EPH receptor A8

NCBI Organism

Homo sapiens

Other Product Names

EEK, EK3, HEK3, ephrin type-A receptor 8, EPH- and ELK-related kinase, EPH- and ELK-related tyrosine kinase, EPH-like kinase 3, hydroxyaryl-protein kinase, protein-tyrosine kinase, tyrosine-protein kinase receptor EEK, tyrosylprotein kinase