CACNA1E Antibody

Product Specifications

Background

Voltage-dependent calcium channels are multisubunit complexes consisting of alpha-1, alpha-2, beta, and delta subunits in a 1:1:1:1 ratio. These channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This gene encodes the alpha-1E subunit of the R-type calcium channels, which belong to the 'high-voltage activated' group that maybe involved in the modulation of firing patterns of neurons important for information processing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

NCBI Gene ID

777

Swiss Prot

Q15878

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 2014-2313 of human CACNA1E (NP_001192222.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Neuroscience, Signal Transduction

Purification

Affinity purification

Positive Control

U-87MG

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 290kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

CACNA1E

Positive Control 2

293T

Positive Control 3

Mouse brain

Positive Control 4

Mouse liver

Positive Control 5

Rat brain

NCBI Official Name

Calcium voltage-gated channel subunit alpha1 E

NCBI Organism

Homo sapiens

Other Product Names

BII, CACH6, CACNL1A6, Cav2.3, EIEE69, gm139, voltage-dependent R-type calcium channel subunit alpha-1E, brain calcium channel II, calcium channel, L type, alpha-1 polypeptide, calcium channel, R type, alpha-1 polypeptide, voltage-dependent calcium channel alpha 1E subunit, voltage-gated calcium channel alpha subunit Cav2.3