PODXL Antibody
Product Specifications
Background
This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin.
NCBI Gene ID
5420
Swiss Prot
O00592
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 287-526 of human PODXL (NP_005388.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Signal Transduction, Stem Cell
Purification
Affinity purification
Positive Control
HeLa
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 95kDa
Fragment
IgG
Symbol
PODXL
Positive Control 2
HepG2
Positive Control 3
SW480
Positive Control 4
HT-1080
Positive Control 5
293T
Positive Control 6
Mouse heart
NCBI Official Name
Podocalyxin-like
NCBI Organism
Homo sapiens
Other Product Names
PODXL, Gp200, MGC138240, PCLP, PC, PCLP-1
Tested Applications
WB, IF
Physical Properties
Liquid
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