SMG6 Antibody
Product Specifications
Background
This gene encodes a component of the telomerase ribonucleoprotein complex responsible for the replication and maintenance of chromosome ends. The encoded protein also plays a role in the nonsense-mediated mRNA decay (NMD) pathway, providing the endonuclease activity near the premature translation termination codon that is needed to initiate NMD. Alternatively spliced transcript variants encoding distinct protein isoforms have been described.
NCBI Gene ID
23293
Swiss Prot
Q86US8
Host
Rabbit
Reactivity
Human, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1160-1419 of human SMG6 (NP_060045.4) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
Affinity purification
Positive Control
HeLa
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=13-455
Calculated Molecular Weight
Observed: 210kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
SMG6
Positive Control 2
Jurkat
Positive Control 3
SW620
Positive Control 4
Rat liver
NCBI Official Name
SMG6 nonsense mediated mRNA decay factor
NCBI Organism
Homo sapiens
Other Product Names
C17orf31, EST1A, SMG-6, hSMG5/7a, telomerase-binding protein EST1A, EST1 telomerase component homolog A, ever shorter telomeres 1A, smg-6 homolog, nonsense mediated mRNA decay factor, telomerase subunit EST1A
Tested Applications
WB
Physical Properties
Liquid
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